BDBM50235945 CHEMBL4068898

SMILES Cc1c(cc(CCF)n1-c1ccc(F)cc1OC(F)F)C(=O)Nc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ABBOJTGMRPEPDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235945   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235945(CHEMBL4068898)
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235945(CHEMBL4068898)
Affinity DataIC50:  6.5nMAssay Description:compound was evaluated for inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50235945(CHEMBL4068898)
Affinity DataIC50:  6.5nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (671 to 984 residues) expressed in African Green Monkey CV-1 cells assessed as inhibition of aldostero...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed