BDBM50235980 2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid::CHEMBL429876::CILENGITIDE::EMD-12192::EMD-121974::[(2S,5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13pentaaza-cyclopentadec-2-yl]-acetic acid::c(RGDfMeV)::cyclo(Arg-Gly-Asp-D-Phe-[N-Me]Val)
SMILES [#6]-[#6](-[#6])-[#6@@H]-1-[#7](-[#6])-[#6](=O)-[#6@@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6]-1=O
InChI Key InChIKey=AMLYAMJWYAIXIA-VWNVYAMZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50235980
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant integrin alpha5beta1 incubated for 1 hr by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]-echistatin from alpha-v-beta-5 integrin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]echistatin from human integrin alpha-V-beta-5 receptor by solid phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18.9nMAssay Description:Displacement of [125I]echistatin from human integrin alpha-V-beta-3 receptor by solid phase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18.9nMAssay Description:Displacement of [125I]-echistatin from alphavbeta3 integrin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of fibronectin binding to soluble alpha5beta1 integrin (unknown origin) after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant integrin alphavbeta3 incubated for 1 hr by ELISA assayMore data for this Ligand-Target Pair