BDBM50236004 CHEMBL4101809

SMILES COc1nc(ccc1-n1cnc(C)c1)C1=NOC[C@@H](N1)c1cc2ccccc2o1

InChI Key InChIKey=YOJYAOMAAVBZQG-MRXNPFEDSA-N

Data  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50236004   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataEC50:  35nMAssay Description:Modulation of amyloid beta 42 in human H4 cells expressing APP751 incubated overnight by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataEC50:  35nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed