BDBM50237457 CHEMBL4097599
SMILES COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1
InChI Key InChIKey=MXAZSKBTKUGBLI-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50237457
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Binding affinity at human progesterone receptor.More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 502nMAssay Description:Binding towards human progesterone receptorMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged glutaminyl cyclase (Ala33 to Leu361 residues) expressed in baculovirus infected Sf21 insect ce...More data for this Ligand-Target Pair
TargetGlutaminyl-peptide cyclotransferase(Mus musculus (mouse))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Effective concentration for antagonistic activity towards human progesterone in CV-1 cellsMore data for this Ligand-Target Pair