BDBM50237798 CHEMBL4105276

SMILES Cc1ccc(cc1-c1cc(ncn1)N1CCOCC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=AAYKOZXUTNQLTC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50237798   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50237798(CHEMBL4105276)
Affinity DataEC50:  700nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed