BDBM50237851 2-biphenyl-4-yl-N-[5-(1,1-dioxo-1lambda*6*-isothiazolidin-2-yl)-1H-indazol-3-yl]-acetamide::CHEMBL402759

SMILES O=C(Cc1ccc(cc1)-c1ccccc1)Nc1n[nH]c2ccc(cc12)N1CCCS1(=O)=O

InChI Key InChIKey=ACNJMIYZGUUYIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237851   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237851(2-biphenyl-4-yl-N-[5-(1,1-dioxo-1lambda*6*-isothia...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237851(2-biphenyl-4-yl-N-[5-(1,1-dioxo-1lambda*6*-isothia...)
Affinity DataIC50:  42nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50237851(2-biphenyl-4-yl-N-[5-(1,1-dioxo-1lambda*6*-isothia...)
Affinity DataIC50:  14nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed