BDBM50238867 CHEMBL4083249
SMILES C[C@@H](c1ccc(F)cc1)n1nnc2cnc3ccc(cc3c12)-c1ccc2ocnc2c1
InChI Key InChIKey=BHKVSOQUPYXVRZ-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50238867
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of recombinant human DYRK1A expressed in insect cells using RRRFRPASPLRGPPK peptide as substrate after 40 mins in presence of [gamma-33P]-...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human JAK2 expressed in insect cells using Poly(Glu:Tyr) as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human FGFR4 expressed in fall armyworm sf21 cells using Poly(Glu:Tyr) as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human MAPK1 expressed in Escherichia coli using MBP as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ULK1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of recombinant human CDK9 expressed in fall armyworm sf21 cells using PDKtide as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CDK6 expressed in fall armyworm sf21 cells using Histone H1 as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human GSK3beta expressed in fall armyworm sf21 cells using Phospho-glycogen synthase peptide-2 as substrate in presence of ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DYRK2More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human DYRK1BMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CLK4 expressed in baculovirus infected Sf21 cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human CLK2 (144 to 498 residues) expressed in insect cells using S6 kinase/Rsk2 substrate peptide 2 in presence of [gamma-3...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human CLK1 expressed in insect cells using ERMRPRKRQGSVRRRV peptide as substrate after 40 mins in presence of [gamma-33P]-A...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DYRK3More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 5.59E+3nMAssay Description:Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGANDMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center For Biotherapy
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human AbL expressed in insect cells using Poly(Glu:Tyr) as substrate in presence of [gamma-32]-ATPMore data for this Ligand-Target Pair