BDBM50239749 2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benzo[d]imidazol-5-yl)piperazin-1-yl)ethanol::5-chloro-2-[(1-ethyl-1-methylpropyl)thio]-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1H-benzimidazole::CHEMBL263918

SMILES CCC(C)(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1

InChI Key InChIKey=WFVCETXISNWHQS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50239749   

TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  0.660nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]naltrindole from human cloned delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]Tyr14-NC from human ORL1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]U-69593 from human cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  0.660nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239749(2-(4-(6-chloro-2-(3-methylpentan-3-ylthio)-3H-benz...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed