BDBM50240174 CHEMBL4100248::US9962398, Compound MST-147

SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2c(F)cccc2F)cc1

InChI Key InChIKey=JNEYBCFAVQEAHD-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240174   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  0.930nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  0.930nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  6.10nMAssay Description:Binding affinity was determined based on the displacement of [125]r-ANF (99-126) from binding sites onmouse fibroblasts (NIH 3T3) cells (Atrionatriur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  6.10nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  8.30nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  158nMAssay Description: CA INHIBITION DATA WITH UREIDOSUBSTITUTED SULFONAMIDES More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Welichem Biotech

US Patent
LigandPNGBDBM50240174(CHEMBL4100248 | US9962398, Compound MST-147)
Affinity DataKi:  158nMAssay Description:Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed