BDBM50240237 CHEMBL4079748
SMILES Fc1cnc(NS(=O)(=O)c2cc(Cl)c(NC[C@H]3NCCC=C3c3ccc(F)cc3)cc2F)s1
InChI Key InChIKey=XLJZYUNHARIFIX-GOSISDBHSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50240237
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Wuxi Apptec (Shanghai)
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human Nav1.7 expressed in CHO-K1 cells at -120 mV holding potential incubated over 5 mins measured at 15 secs interval by Qpatch clamp ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using Phenacetin as substrate preincubated for 10 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate preincubated for 10 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair