BDBM50240715 (S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid::CHEMBL106820::N5-(1-iminobut-3-enyl)-L-ornithine

SMILES CC=CC(N)=NCCC[C@H](N)C(O)=O

InChI Key InChIKey=RIIDRLUFTKIGSQ-ZETCQYMHSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240715   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  100nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed