BDBM50240772 (1R,2S)-(-)-2-phenylcyclopropylamine::(1R,2S)-2-phenylcyclopropanamine::(tranylcypromine)2-Phenyl-cyclopropylamine::2-Phenyl-cyclopropylamine::CHEMBL1179::Parnate::TRANYLCYPROMINE::TRANYLCYPROMINE HYDROCHLORIDE::US10836743, Compound TCP::US8993808, Tranylcypromine::US9180183, Tranylcypromine::cid_2723716::rel-Tranylcypromine

SMILES N[C@@H]1C[C@H]1c1ccccc1

InChI Key InChIKey=AELCINSCMGFISI-DTWKUNHWSA-N

Data  15 KI  84 IC50  4 Kd  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240772   

TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  8.80E+3nMAssay Description:Binding affinity against human Alpha-1d adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  3.06E+4nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using H3K4me1 peptide as substrate preincubated for 15 mins with e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of recombinant human MAOA incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50240772((1R,2S)-(-)-2-phenylcyclopropylamine | (1R,2S)-2-p...)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human MAOB incubated for 15 mins measured after 30 mins by luminescence-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed