BDBM50240884 CHEMBL4085572

SMILES Cc1csc(COc2cc(=O)n3[C@H](Cc4ccccc4)COCc3n2)n1

InChI Key InChIKey=MAHIHFKKDJNURQ-OAHLLOKOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240884   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50240884(CHEMBL4085572)
Affinity DataIC50:  5.70nMAssay Description:Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed