BDBM50241151 CHEMBL4087681

SMILES CC(C)(C)c1ccc(cc1)C(=O)NCc1ccc(NC(=O)C(F)(F)F)cc1Cl

InChI Key InChIKey=XXQQYBWXNCCULQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241151   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241151(CHEMBL4087681)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile acid receptor(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50241151(CHEMBL4087681)
Affinity DataEC50:  14nMAssay Description:Transactivation of human FXR expressed in human HeLa cells co-expressing BSEP after 24 hrs by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed