BDBM50241346 10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tetrahydro-4H-1-oxa-9-aza-anthracene-3-carboxylic acid ethyl ester::CHEMBL398628::ethyl 5-amino-4-(4-methoxyphenyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinoline-3-carboxylate

SMILES CCOC(=O)C1=C(C)Oc2nc3CCCCc3c(N)c2C1c1ccc(OC)cc1

InChI Key InChIKey=NJPVUJVNAWTZJX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50241346   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  868nMAssay Description:Inhibition of Electrophorus electricus acetylcholinesterase preincubated with compound for 10 mins using acetylcholine iodide as substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  870nMAssay Description:Inhibition of Electrophorus electricus AChE by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  182nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Hospital Universitario De La Princesa

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate by Ellman's methodsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Hospital Universitario De La Princesa

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Bos taurus (bovine))
Hospital Universitario De La Princesa

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  870nMAssay Description:Inhibition of bovine erythrocytes AChE using acetylthiocholine iodide as substrate by Ellman's methodsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241346(10-Amino-4-(4-methoxy-phenyl)-2-methyl-5,6,7,8-tet...)
Affinity DataIC50:  870nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed