BDBM50241362 5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL250880

SMILES CC(C)c1cc(Oc2c(Cl)cc3nc(cc(O)c3c2Cl)C(O)=O)ccc1O

InChI Key InChIKey=REFNRSMJTOAWKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241362   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)
Affinity DataIC50:  15.1nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50241362(5,7-dichloro-6-(4-hydroxy-3-isopropylphenoxy)-4-ox...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human TRalpha1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed