BDBM50242266 CHEMBL4067185

SMILES C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1C[C@H](C[C@H]1C(O)=O)NC(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=OABPNHDJHMUHTK-HVEDROQYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50242266   

TargetProlyl endopeptidase(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of PPCE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  155nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Mus musculus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  217nMAssay Description:Inhibition of ob/ob mouse plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  255nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Mus musculus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  58nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  4.40E+4nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of NEP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  158nMAssay Description:Inhibition of human plasma ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242266(CHEMBL4067185)
Affinity DataIC50:  334nMAssay Description:Inhibitory activity against human renin inhibition (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed