BDBM50242274 CHEMBL4090635

SMILES CCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1C[C@H](C[C@H]1C(O)=O)NC(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=SVXBTHULZGXAEU-PYVLESRRSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50242274   

TargetProlyl endopeptidase(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PPCE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of NEP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Mus musculus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  7.17E+3nMAssay Description:Inhibition of ob/ob mouse plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Mus musculus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of ob/ob mouse plasma ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  279nMAssay Description:Inhibition of human plasma ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested in vitro for binding affinity against human carbonic anhydrase II; (ki*10e-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  4.17E+3nMAssay Description:Inhibition of Wistar rat plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  102nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of Wistar rat plasma ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Ranbaxy Laboratories

Curated by ChEMBL
LigandPNGBDBM50242274(CHEMBL4090635)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity to HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed