BDBM50242419 6-Deoxy-L-galactose::6-deoxy-L-galactopyranoseL-fucopyranose::CHEMBL469449::L-fucopyranose::L-fucose

SMILES C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O

InChI Key InChIKey=SHZGCJCMOBCMKK-DHVFOXMCSA-N

Data  3 KI  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50242419   

TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  3.00E+5nMAssay Description:Compound was tested for inhibitory activity (competitive) against alpha-L-fucosidase from bovine kidneyMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTissue alpha-L-fucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition constant against Alpha-FucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKi:  6.70E+6nMAssay Description:Displacement of [125I]-Man30-BSA from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)TBA
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  910nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCD209 antigen(Homo sapiens (Human))
University Of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50242419(6-Deoxy-L-galactose | 6-deoxy-L-galactopyranoseL-f...)
Affinity DataIC50:  2.95E+6nMAssay Description:Displacement of biotinylated HIV1 gp120 from DC-SIGN receptor carbohydrate recognition domain (unknown origin) after 2 hrs by solid-phase competitive...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed