BDBM50242977 CHEMBL500862::Cepharanthine::cepharantine

SMILES COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(Oc5c6OCOc6cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

InChI Key InChIKey=YVPXVXANRNDGTA-VMPREFPWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242977   

TargetReplicase polyprotein 1ab(2019-nCoV)
Institut Pasteur Korea

LigandPNGBDBM50242977(CHEMBL500862 | Cepharanthine | cepharantine)
Affinity DataIC50:  4.47E+3nMAssay Description:Ten-point DRCs were generated for each drug. Vero cells were seeded at 1.2 × 104 cells per well in DMEM, supplemented with 2% FBS and 1× ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50242977(CHEMBL500862 | Cepharanthine | cepharantine)
Affinity DataIC50:  1.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed