BDBM50243173 CHEMBL487445::N-(2-Benzoyl-phenyl)-4-[3-(3-piperidin-1-yl-propyl)-ureido]-benzenesulfonamide

SMILES O=C(NCCCN1CCCCC1)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)c1ccccc1

InChI Key InChIKey=KZLRUEFFWHYSAT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243173   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50243173(CHEMBL487445 | N-(2-Benzoyl-phenyl)-4-[3-(3-piperi...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]Lys0-des-Arg9-BK at human bradykinin B1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50243173(CHEMBL487445 | N-(2-Benzoyl-phenyl)-4-[3-(3-piperi...)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243173(CHEMBL487445 | N-(2-Benzoyl-phenyl)-4-[3-(3-piperi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of MK-499 from human ERG channel in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed