BDBM50243327 1-[4-(7-Amino-3-thiophen-3-yl-pyrazolo[1,5-a]pyrimidin-6-yl)-phenyl]-3-m-tolyl-urea::CHEMBL452522

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cnc3c(cnn3c2N)-c2ccsc2)c1

InChI Key InChIKey=AQDKLUJYKQRNDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243327   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243327(1-[4-(7-Amino-3-thiophen-3-yl-pyrazolo[1,5-a]pyrim...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50243327(1-[4-(7-Amino-3-thiophen-3-yl-pyrazolo[1,5-a]pyrim...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed