BDBM50243342 4-(2-{[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]amino}ethyl)-3-isopropoxy-4-biphenylcarboxylic acid::CHEMBL453047

SMILES CC(C)Oc1cc(ccc1C(O)=O)-c1ccc(CCN[C@@H](C)[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=WVYCDLWTGGHFDH-SIBVEZHUSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243342   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243342(4-(2-{[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]am...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant beta2 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243342(4-(2-{[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]am...)
Affinity DataEC50:  780nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243342(4-(2-{[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]am...)
Affinity DataEC50:  0.810nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Canis familiaris)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243342(4-(2-{[(1S,2R)-2-Hydroxy-1-methyl-2-phenylethyl]am...)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed