BDBM50243414 CHEMBL4084757
SMILES Fc1cc2cc[nH]c(=O)c2cc1NS(=O)(=O)c1ccc(cc1)C#N
InChI Key InChIKey=QCEOCULEQLXXFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50243414
Affinity DataEC50: 1.81E+3nMAssay Description:Inhibition of AICARFT in human NCI-H460 cells assessed as increase in ZMP levels using low folate media after 16 hrs by LC-MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 723nMAssay Description:Inhibition of human full length N-terminal His-tagged AICARFT expressed in Escherichia coli BL21 (DE3) using ZMP/10-formyltetrahydrofolate as substra...More data for this Ligand-Target Pair