BDBM50243618 (2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2-(furan-2-yl)phenyl)ethoxy)pyrimidin-4-yl)phenyl)propanoic acid::CHEMBL471564

SMILES N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2ccccc2-c2ccco2)C(F)(F)F)nc(N)n1)C(O)=O

InChI Key InChIKey=FSCFHAGDJFDLFG-HXBUSHRASA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243618   

TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  800nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  48nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed