BDBM50243655 (2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3-(furan-2-yl)thiophen-2-yl)ethoxy)pyrimidin-4-yl) phenyl)propanoic acid::CHEMBL512353

SMILES N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2sccc2-c2ccco2)C(F)(F)F)nc(N)n1)C(O)=O

InChI Key InChIKey=MCBFYQXJYBEXHO-OOJLDXBWSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243655   

TargetTryptophan 5-hydroxylase 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataEC50:  1.19E+3nMAssay Description:Inhibition of TPH2 in human BON cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataEC50:  63nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataIC50:  54nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed