BDBM50243761 4-(1H-Indol-3-yl)-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL529663
SMILES COc1cc(cc(OC)c1OC)C1=C(CNC1=O)c1c[nH]c2ccccc12
InChI Key InChIKey=YTFRDKYCZHOSMM-UHFFFAOYSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50243761
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human recombinant Aurora BMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant INS-RMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human recombinant EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant COTMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant IGF1RMore data for this Ligand-Target Pair