BDBM50243845 3,5-Dichloro-N-[1-(4-methyl-benzyl)-piperidin-4-ylmethyl]-benzamide::CHEMBL488295

SMILES Cc1ccc(CN2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)cc1

InChI Key InChIKey=VRVONDCSZOZMRU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243845   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243845(3,5-Dichloro-N-[1-(4-methyl-benzyl)-piperidin-4-yl...)
Affinity DataIC50:  135nMAssay Description:Antagonist activity at human ERG by voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243845(3,5-Dichloro-N-[1-(4-methyl-benzyl)-piperidin-4-yl...)
Affinity DataIC50:  135nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50243845(3,5-Dichloro-N-[1-(4-methyl-benzyl)-piperidin-4-yl...)
Affinity DataIC50:  281nMAssay Description:Inhibition of T-type calcium channel alpha1I (unknown origin) by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed