BDBM50243878 3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2Hpyrrole-2-one::CHEMBL521201

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1)c1c[nH]c2ccccc12

InChI Key InChIKey=FQCMIMYFHWLFTJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50243878   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant Aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243878(3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-d...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human recombinant CDK4/cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed