BDBM50243878 3-(1H-Indol-3-yl)-4-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2Hpyrrole-2-one::CHEMBL521201
SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1)c1c[nH]c2ccccc12
InChI Key InChIKey=FQCMIMYFHWLFTJ-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50243878
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant Aurora BMore data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human recombinant Aurora AMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant CDK4/cyclin D1More data for this Ligand-Target Pair