BDBM50243881 4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trimethoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL519590

SMILES COCn1cc(C2=C(C(=O)NC2)c2cc(OC)c(OC)c(OC)c2)c2ccccc12

InChI Key InChIKey=FXOKLOPGTMWYLS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50243881   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243881(4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243881(4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human recombinant FAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243881(4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243881(4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50243881(4-[1-(Methoxymethyl)-1H-indol-3-yl]-3-(3,4,5-trime...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed