BDBM50244032 3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5-dihydro-2H-pyrrole-2-one::CHEMBL507056

SMILES COc1ccc(cc1)C1=C(C(=O)NC1)c1cn(C)c2ccccc12

InChI Key InChIKey=OFLIHYXEJVKHNC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50244032   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of human recombinant SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of human recombinant TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50244032(3-(N-Methyl-1H-indol-3-yl)-4-(4-methoxyphenyl)-1,5...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed