BDBM50244034 3-ethoxy-9H-pyrido[3,4-b]indole::CHEMBL498936

SMILES CCOc1cc2c(cn1)[nH]c1ccccc21

InChI Key InChIKey=FNNPSIGQQWCKKB-UHFFFAOYSA-N

Data  5 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50244034   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKi:  6.43nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKi:  25.1nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKi:  28.2nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKi:  826nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244034(3-ethoxy-9H-pyrido[3,4-b]indole | CHEMBL498936)
Affinity DataKd:  826nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed