BDBM50245459 4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-yl)-propyl]pyrrolo[3,4-c]carbazole-1,3(2H,6H )-dione::6-(3-(1H-tetrazol-5-yl)propyl)-4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL471329

SMILES Oc1ccc2n(CCCc3nnn[nH]3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl

InChI Key InChIKey=VUNCSLBXILQSKB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50245459   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdc2 Tyr15 phosphorylation in human HT29 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50:  630nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245459(4-(2-Chlorophenyl)-9-hydroxy-6-[3-(1H-tetrazol-5-y...)
Affinity DataIC50: >3.40E+3nMAssay Description:Inhibition of Cdc2 Tyr15 phosphorylation in human HT29 cells by Western blotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed