BDBM50245497 9-Hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::9-hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

SMILES COc1ccccc1-c1cc2n(CCCO)c3ccc(O)cc3c2c2C(=O)NC(=O)c12

InChI Key InChIKey=AOGOZJCRIFBTTN-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245497   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50245497(9-Hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245497(9-Hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245497(9-Hydroxy-6-(3-hydroxypropyl)-4-(2-methoxyphenyl)-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair