BDBM50246035 2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)methyl]-1,2,4-oxadiazol-5-yl}thiophen-2-yl)ethanone::2,2,2-trifluoro-1-(5-(3-((thiophen-2-ylsulfonyl)methyl)-1,2,4-oxadiazol-5-yl)thiophen-2-yl)ethanone::CHEMBL471174

SMILES FC(F)(F)C(=O)c1ccc(s1)-c1nc(CS(=O)(=O)c2cccs2)no1

InChI Key InChIKey=GJBRKLVHIOIDHV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50246035   

TargetHistone deacetylase 4(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  35nMAssay Description:Inhibition of His-tagged HDAC4 catalytic domain (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  520nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  520nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50246035(2,2,2-Trifluoro-1-(5-{3-[(thiophen-2-ylsulfonyl)me...)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed