BDBM50246147 CHEMBL513593::N-(4-(3-chloro-4-methoxybenzylamino)-7-methoxy-8-(2-(piperidin-1-yl)ethyl)quinazolin-6-yl)-2,2,2-trifluoroacetamide

SMILES COc1ccc(CNc2ncnc3c(CCN4CCCCC4)c(OC)c(NC(=O)C(F)(F)F)cc23)cc1Cl

InChI Key InChIKey=IBIOIBXTTFIPRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50246147   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246147(CHEMBL513593 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  19nMAssay Description:Inhibition of bovine PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50246147(CHEMBL513593 | N-(4-(3-chloro-4-methoxybenzylamino...)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of human recombinant PDE11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed