BDBM50246332 2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-5-methoxy-3-methylquinazolin-4(3H)-one::CHEMBL453653
SMILES COc1cccc2nc(-c3ccc(OC4CCN(CC4)C4CCC4)cc3)n(C)c(=O)c12
InChI Key InChIKey=HVRHVFJBNXLKGN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50246332
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in LMtk- cellsMore data for this Ligand-Target Pair