BDBM50246646 (R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-N-omega-propanoylargininamide::CHEMBL446342::CHEMBL470495

SMILES CCC(=O)NC(N)=NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1

InChI Key InChIKey=DTIOXMCBTYZRGU-RUZDIDTESA-N

Data  5 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50246646   

TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of Dy-635-pNPY from human neuropeptide Y5 receptor expressed in HEC-1B cells by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Dy-635-pNPY from human neuropeptide Y2 receptor expressed in CHO cells coexpressing Galphaqi5 and aequorin by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of Cy5-[K4]-hPP from human neuropeptide Y4 receptor expressed in CHO cells coexpressing Galphaqi5 and aequorin by flow cytometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human SK-N-MC cells by kinetic experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.20nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to neuropeptide Y1 receptor in human MCF7 cells by kinetic experimentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50246646((R)-Nalpha-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl...)
Affinity DataKd:  1.20nMAssay Description:Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed