BDBM50246763 CHEMBL4094760
SMILES C1CC(CCO1)c1c[nH]c2ncnc(N[C@H]3CC[C@H](CC3)N3CCOCC3)c12
InChI Key InChIKey=DJVYXMINSBMUHH-CALCHBBNSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50246763
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of IRAK4 in human KARPAS299 cells assessed as reduction in IL-1 stimulated IRAK4 phosphorylation at Thr345/Ser346 residues preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of kinase tracer 236 binding to recombinant human full-length GST-tagged IRAK3 expressed in insect cells by Lanthascreen Eu kinase binding...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using 5-FAM-KKKVSRSGLYRS...More data for this Ligand-Target Pair