BDBM50247394 8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoline-2-carboximidic acid phenyl ethyl ester::CHEMBL453133

SMILES CCn1cnc2ccc3nc(sc3c2c1=O)C(=N)OCCc1ccccc1

InChI Key InChIKey=PFWCEPWUHBDYJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50247394   

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50247394(8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoli...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50247394(8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoli...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GSK3alpha/beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50247394(8-Ethyl-9-oxo-8,9-dihydro-thiazolo[5,4-f]quinazoli...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed