BDBM50247572 (R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrrolidin-1-yl)-N-hydroxypropanamide::CHEMBL515390

SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccc(cc1)-c1ccccc1)C(=O)NO

InChI Key InChIKey=MCVFKNHXPZRVBQ-VLIAUNLRSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247572   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50247572((R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrroli...)
Affinity DataKi:  35nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50247572((R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrroli...)
Affinity DataKi:  82nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50247572((R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrroli...)
Affinity DataKi:  2.29E+3nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50247572((R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrroli...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50247572((R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrroli...)
Affinity DataIC50:  1.30E+4nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed