BDBM50247721 4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide::CHEMBL511186

SMILES NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=RXAAVLURIXEENO-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50247721   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  290nMAssay Description:Inhibition of human recombinant CA9 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  870nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of calf intestinal alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Bos taurus (Cattle))
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of bovine kidney non-specific alkaline phosphatase using CDP-star chemiluminescent substrate assessed as change in luminescence by spectro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Forman Christian College (A Chartered University)

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50:  215nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed