BDBM50247827 5-(4-methoxyphenyl)-4-p-tolylisothiazole::CHEMBL514950
SMILES COc1ccc(cc1)-c1sncc1-c1ccc(C)cc1
InChI Key InChIKey=KPYJYWIFJYUIBB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50247827
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of COX2 in LPS-stimulated human bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLCMore data for this Ligand-Target Pair