BDBM50248037 (R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-methylfuran-2-yl)propylamino)-1,2,5-thiadiazol-3-ylamino)benzamide::CHEMBL510437

SMILES CC(C)[C@@H](Nc1nsnc1Nc1cccc(C(=O)N(C)C)c1O)c1ccc(C)o1

InChI Key InChIKey=UNPQYPMTWSIZRR-MRXNPFEDSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248037   

TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  15nMAssay Description:Displacement of IL8 from CXCR1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of IL8 from CXCR2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]CXCL1 from CXCR2 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50248037((R)-2-hydroxy-N,N-dimethyl-3-(4-(2-methyl-1-(5-met...)
Affinity DataIC50:  3.91E+3nMAssay Description:Displacement of [125I]CXCL8 from CXCR1 receptor in human PMN assessed as myeloperoxidase releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed