BDBM50248146 CHEMBL461109::N2-(4-(benzo[d]thiazol-2-yl)phenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

SMILES Cc1cc(Nc2ccnc(Nc3ccc(cc3)-c3nc4ccccc4s3)n2)[nH]n1

InChI Key InChIKey=KOFCLQKGQYBGNB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248146   

TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248146(CHEMBL461109 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248146(CHEMBL461109 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248146(CHEMBL461109 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248146(CHEMBL461109 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248146(CHEMBL461109 | N2-(4-(benzo[d]thiazol-2-yl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed