BDBM50248147 CHEMBL461110::N2-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

SMILES COc1cc(Nc2nccc(Nc3cc(C)n[nH]3)n2)ccc1-c1nc2ccccc2s1

InChI Key InChIKey=HSMLVQPVLGLUCI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50248147   

TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR3 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ErbB2 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248147(CHEMBL461110 | N2-(4-(benzo[d]thiazol-2-yl)-3-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed