BDBM50248254 (R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpiperazin-1-yl)methyl)quinoline::CHEMBL473756

SMILES C[C@@H]1CN(Cc2ccnc3ccccc23)CCN1S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=VEOGALWAYZUFRM-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248254   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248254((R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpip...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248254((R)-4-((4-(4-tert-butylphenylsulfonyl)-3-methylpip...)
Affinity DataIC50:  78nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed