BDBM50248256 3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N-hydroxyacrylamide::CHEMBL474349::US10201527, Compound 57::US10736881, Compound 57

SMILES CN(C)CCCCn1c(CCc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=AAZSJWCWXIAUHW-NTCAYCPXSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248256   

TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248256(3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248256(3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo...)
Affinity DataIC50:  153nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248256(3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo...)
Affinity DataIC50:  153nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent