BDBM50248370 (2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,1,2-tetrafluoropropan-2-yl)phenylsulfonyl)piperazine::CHEMBL491152

SMILES C[C@@H]1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(cc1)C(C)(F)C(F)(F)F

InChI Key InChIKey=MMYLQVAQWGZWTJ-QRIPLOBPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248370   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248370((2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,...)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248370((2R)-2-methyl-4-(2-(pyridin-4-yl)ethyl)-1-(4-(1,1,...)
Affinity DataIC50:  71nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed