BDBM50248416 CHEMBL443906::N-(3-(benzo[d]thiazol-2-yl)phenyl)-9H-purin-6-amine

SMILES N(c1cccc(c1)-c1nc2ccccc2s1)c1ncnc2nc[nH]c12

InChI Key InChIKey=SRCAIQMBBDVLGX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50248416   

TargetInsulin receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  840nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50248416(CHEMBL443906 | N-(3-(benzo[d]thiazol-2-yl)phenyl)-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed